RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20 AUG 90

File: 120396_sep96_decls54_0016.txt
Page: 0016
Total Pages: 16

Subject: RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20 AUG 90          

Unit: OTSG        

Parent Organization: HSC         

Box ID: BX003201

Folder Title: OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT                            

Document Number:          1

Folder SEQ  #:         45







                III SPECIF'IC LABORATORY DIAGNOSIS
                None available. Acute blood and tissue samples should be collected, but
          identification of toxins is uncertain and a research issue. Mouse toxicity is one
          test, and ELISA assays for alpha and other toxins are feasible.
                The enterotoxin can be detected in fecal samples from human food-
          poisoning cases, and bacteria are readily cultured from clinical samples.
                IV THERAPY
                No specific treatment is available for perfrineens intoxication.
          Humans with enteritis necroticans have been treated with antitoxin with some

          success.
                The organism itself is sensitive to penicillin, and, consequently, this is the
          current drug of choice. Recent data indicate that clindamycin or rifampin may
          suppress toxin production, and provide superior results in animal models.
                V PROPHYLAXIS
                There is no available prophylaxis for C. 12erfringens intoxication.
          Toxoids are being used to prevent enteritis necroticans in humans, and
          veterinary toxoids are in wide use.








                                               16        DRAFT

Document 16 f:/Week-36/BX003201/OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT/response to the biological warfare bw threat 20 :11229616342212
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003201
Unit = OTSG
Parent Organization = HSC
Folder Title = OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT
Folder Seq # = 45
Subject = RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 22-NOV-1996