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File: 123096_sep96_decls23_0051.txt
Page: 0051
Total Pages: 52

Subject: DIAGNOSIS AND TREATMENT OF DISEASES OF IMPORTANCE               

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DIAGNOSIS AND TREATMENT OF DISEASES  1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS                

Document Number:          1

Folder Seq  #:         88








                                                                                                                                                                                   PARALYSIS IN THE BWICW SETTING
                                                       SECTION IV                                                                                        The differential diagnosis must include both botulinum and nerve agent intoxications.
                                                                                                                                                         a: Nerve agent is rapid in onset (niinuws to 1-2 hr). A rigid @ysis develop& with
                                                             TABLE I                                                                            parasympathetic excess (salivation, miosis, sweating, involuntary defecation, and urinafion);
                         DTFFERENTIATION AMONG NERVE AGENT, ATROPINE,                                                                           central nervous system dysfunction and death soon follow. If exposure is by aerosol or
                                         AND BOTULINUM INTOXICATIONS                                                                            vapor, constficted pupils, rhinoffhea, and bronch@nstriction also occur.
                                                                                                                                                         b: Botutinum toxin is slower in onset (3 hr to several days). Descending paralysis
                                     BOTULINUM TOXIN                    NERVE AGENT                       ATROPINE                              (bulbar to extremities to respiratory) and parasympathetic blockade (dry mouth, pupillary
ating) are characteristic. Paralysis,
                                                                   agitation, coma,              excitation, agitation,                         nausea, vomiting, and diarrhea may, however, occur after exposure to either nerve agent or
                                                                   sei@ures                      irritability, coma                             botulinum toxin. Central signs (confusion, seizure, coma) @ nine after botulinum, but
                                                                                                                                                common after nerve agent intoxication.
            OphthalMOlOgiC      Dilated and fixed pupils,          Constricted ouoils, dim       Weak effects if sual                                    c:   Andcholinergics such as atropine can, of course, muse central nervous system
            Abnormalities       distorted blurred vision,          vision (if vapor or aerosol   doses given causing                            changes such as agitation, confusion, and hallucinations u well as dry mouth, dry skin, and
                                Ptosis, extraocular muscle         exposure), linte if any       Pupilla@ dilation and
                                paralysis                          change it exposed via         paralysis of                                   constipation. These changes could easily obscure the correct diagnosis in a soldier who used
                                                                   skin                          accommodation                                  his injmtor even without exposure to an agent.

            Pa,.Iy              Flaccid Paralysis. Early           Rigid paralysis ith           None of significance
                                bulbar signs (dvsphonia,           t.itching, jerking.
                                dysphagia) descending to           Sei.ures.
                                upper and lo@e,
                   extremities. Respiratory
                                failure.


            Autonomic           Dry mouth and skin,                Excess sali@alion,            Dry mouth and skin,
            Findings            constipation, ileus, rin.@         increased sweating,           constipation. ile,s,
                                retention. Early emesis and        involuntary defecation        urinary etentio.. E,,Iy
                                diarrhea aft,, food                and Uli.ation. Severe         emesis and diarrhea
                                i@gestio@.                         'hi@ovhea and                 after food ingestion,
                                                                   bronchoconstriction
                                                                   occur if exposure is by
                                                                   inhalation.


            Onset               3-36 hours by inhalation           1-10 minutes by               Minutes after injection,
                                exposure. Nei b,,,bed              inhalation exposure; 1-2      can be exacerbated by
                                through intact skin; 1 2-72        hours by dermal               dehydration and heat
                                hours onset by r,l                 exposure                      exposure
                                exposure










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Document 52 f:/Week-36/BX003203/DIAGNOSIS AND TREATMENT OF DISEASES 1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS/diagnosis and treatment of diseases of importanc:12179609281524
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DIAGNOSIS AND TREATMENT OF DISEASES 1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS
Folder Seq # = 88
Subject = DIAGNOSIS AND TREATMENT OF DISEASES OF IMPORTANC
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996