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Subject: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS       

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS                                       

Document Number:          1

Folder Seq  #:         21




                                 UNCLASSIFIED
                                 @ -1
                                       -, JL




          incidence of inhalation anthrax. Limited human data suggest that

          after completion of the first three doses of the recommended six-

          dose primary series protection against both cutaneous and

          inhalation anthrax in afforded. Studies in rhesus monkeys indicate

          that good protection is afforded after two doses (10-16 days apart)

          for up to 2 years. It is likely that two doses in humans is

          protective as well, but there is too little information to draw

          firm conclusions. As with all vaccines, the degree of protection

          depends upon the magnitude of the challenge dose; vaccine-induced

          protection is undoubtedly overwhelmed by extremely high spore

          challenge.



               In the present setting, three doses of the vaccine is

          recommended for prophylaxis against inhalation anthrax.

          Contraindications for use are sensitivity to vaccine components

          (formalin, alum, benzethonium chloride) and/or history of

          clinical anthrax. Reactogenicity is mild to moderate: up

          to 6% of recipients will experience mild discomfort at the

          inoculation site for up to 72 hours (tenderness, erythema,

          edema, pruritus), while a smaller proportion (




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Document 109 f:/Week-36/BX003203/DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS/detection of medical defense against biological :1217960927452

Control Fields 17

File Room = sep96_declassified

File Cabinet = Week-36

Box ID = BX003203

Unit = OTSG

Parent Organization = HSC

Folder Title = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS

Folder Seq # = 21

Subject = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL 

Document Seq # = 1

Document Date = 

Scan Date = 

Queued for Declassification = 01-JAN-1980

Short Term Referral = 01-JAN-1980

Long Term Referral = 01-JAN-1980

Permanent Referral = 01-JAN-1980

Non-Health Related Document = 01-JAN-1980

Declassified = 17-DEC-1996