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File: 123096_sep96_decls1_0037.txt
Page: 0037
Total Pages: 109

Subject: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS       

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS                                       

Document Number:          1

Folder Seq  #:         21






                                     UNCLASSIFIED
                                      @@47,Rf;!Af

           and severe systemic reactions (anaphylaxis, which precludes

           additional vaccination) are rare. The vaccine should be stored

           at refrigerator temperature (not frozen).

               ANTIBIOTICS

               Choice of antibiotics for prophylaxis is guided by the same

           principles as that for treatment; i.e., it is relatively easy to

           produce a penicillin-resistant organism in the laboratory, and

           possible, albeit somewhat more difficult, to induce tetracycline

           resistance. Therefore, if there is information indicating a

           biological weapon attack, prophylaxis with ciprofloxacin (500 mg po

           bid), or doxycyline (100 mg po bid) should begin. If unvaccinated,

           a single 0.5 ml dose of vaccine should also be given

           subcutaneously. Should the attack be confirmed as anthrax,

           antibiotics should be continued for at least 4 weeks in all

           exposed. In addition, two 0.5 ml doses of vaccine should be given

           2 weeks apart in the unvaccinated; those previously vaccinated with

           fewer than three doses should receive a single 0.5 ml booster,

           while vaccination probably is not necessary for those who have

           received the entire three-dose primary series. Upon

           discontinuation of antibiotics, patients should be closely

           observed; if clinical signs of anthrax occur, patients should be

           treated as indicated above. If vaccine is not available,

           antibiotics should be continued beyond 4 weeks until the patient
           can be closely obarved upon diiscontinuation of therapy.


                                         12
                                   UNCLASSIFIED
                                                        -A@@,IFIED -,Y: @AIJLTIr'LF SOUt@CF-5;
             @lil@   C)ADR

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Document 109 f:/Week-36/BX003203/DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS/detection of medical defense against biological :1217960927452
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS
Folder Seq # = 21
Subject = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996