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File: 120396_sep96_decls54_0013.txt
Subject: RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20 AUG 90
Unit: OTSG
Parent Organization: HSC
Box ID: BX003201
Folder Title: OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT
Document Number: 1
Folder SEQ #: 45
STAPHYLOCOCCAL ENTEROTOXIN B
I CLINICAL SYNDROME
Staphylococcal enterotoxin B (SEB), produced by SW-hylococcus aureus,
causes food poisoning when ingested.
A biowarfare attack with aerosol delivery of SEB to the respiratory tract
produces a distinct syndrome causing significant morbidity and potential
mortality.
Clinical Features: The disease begins 1 to 6 hours after exposure with the
sudden onset of fever, chills, headache, myalgia, and nonproductive cough. In
more severe cases, dyspnea and retrostemal chest pain may also be present.
Fever, which may reach 103-106 F, has lasted 2-5 days, but cough may persist
1 to 4 weeks. In many patients, nausea, which may be severe, and vomiting
will also occur. Physical findings are often unremarkable. Conjunctival
injection may be present, and in the most severe cases, signs of pulmonary
edema would be expected. The chest X-ray is generally normal, but in severe
cases, there will be increased interstitial markings, atelectasis, and possibly
overt pulmonary edema. In moderately severe laboratory exposures, lost duty
time has been less than 2 weeks, but, based upon animal data, it is anticipated
that severe exposures will result in fatalities.
II DIAGNOSIS
Laboratory findings are non-contributory except for a neutrophilic
leukocytosis and elevated erythrocyte sedimentation rate.
In foodbome SEB intoxication, fever and respiratory involvement are not
seen, and gastrointestinal symptoms are prominent.
III SPECMC LABORATORY DIAGNOSIS
13
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Document 16 f:/Week-36/BX003201/OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT/response to the biological warfare bw threat 20 :11229616342212
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003201
Unit = OTSG
Parent Organization = HSC
Folder Title = OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT
Folder Seq # = 45
Subject = RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 22-NOV-1996